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Image Search Results
Journal: American Journal of Physiology - Heart and Circulatory Physiology
Article Title: Targeted ablation of cardiac sympathetic neurons reduces the susceptibility to ischemia-induced sustained ventricular tachycardia in conscious rats
doi: 10.1152/ajpheart.00955.2009
Figure Lengend Snippet: One-second analog recordings of arterial pressure and the electrocardiogram (ECG) before coronary artery occlusion (preoccclusion), at 4 min of occlusion, and at the onset of sustained ventricular tachycardia and reduction in arterial pressure (prearrhythmia) from two rats. Each rat received bilateral stellate injections of cholera toxin B (CTB; top) or CTB-saporin (SAP; bottom). The time from coronary artery occlusion to the onset of sustained ventricular tachycardia and reduction in arterial pressure was defined as the ventricular arrhythmia threshold. Coronary artery occlusion was documented by ST segment elevation. Note the higher ST segment elevation in the CTB rat compared with the CTB-SAP rat at 4 min of occlusion. CTB-SAP rats had a significantly longer ventricular arrhythmia threshold compared with control and CTB rats. In this example, the sustained ventricular tachycardia and reduction in arterial pressure occurred at 4 min and 12 s in the CTB rat compared with 10 min in the CTB-SAP rat.
Article Snippet: The ECGs were analyzed offline to measure the ST segment elevation (voltage difference between the baseline and J point) using the
Techniques: